Expression of MPO and TGF-β1 in Ulcerative colitis / 中国医师杂志
Journal of Chinese Physician
;
(12): 31-33, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-395934
ABSTRACT
Objective To explore the expression and effect of MP0 and TGF-β1 in ulcerative colitis tissues.Methods The expressions of MPO and TGF-Bl in colonal tissue specimens were determined by immunohistochemistry(two step method)in 37 cases of ulcerative colitis,10 crohng disease and 20 normal mucosa.Results The positive rates of MPO and TGF.B1 were 10%and 20.0%in the normal mucosa,55.0%and 35.O%in crohn's disease,and 89.2%and 86.5%in ulcerative colitis.Expression of MPO and TGF-β1 in the ulcerative colitis were higIIer than that in crohn's disease and normal mucosa(P<0.05),there was correlation between MPO and TGF-β1(r=O.51,P<0.05).Conclusion MPO and FGF-β1 are involved in the pathology of UC,and detection of MPO and TGFβ1 can provide some value to evaluate the conditions of UC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Chinese Physician
Año:
2009
Tipo del documento:
Artículo
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