Primary study of carotid atherosclerosis plaque biomechnics using ultrasonic velocity vector imaging in patients with coronary artery disease / 中华超声影像学杂志

ABSTRACT

Objective To assess the changes of the velocity,strain and strain rate on the corresponding vascular of plaque and without plaque,bard plaque and soft plaque,the cupular part of fiber cowl and shoulder of plaque.Methods Eighty-six patients with coronary artery disease(CAD)according to the results of coronary arteriography and 50 normal subjects underwent the high frequency ultrasound,and carotid artery intima media thickness(IMT)was detected.The velocity,strain and stain rate of carotid were obtained by velocity vector imaging(VVI)speckle tracking technique.Results The level of IMT in CAD patients was higher than that in normal control(P＜0.05).The systolic maximum velocity of carotid with normal contract was higher significantly than that of carotid without plaque with CAD(P＜0.05).The systolic maximum velocity and strain rate of soft plaque in carotid atherosclerosis were higher significantly than those of hard plaque(P＜0.001,P＜0.05).The maximum velocity and strain rate of fabric cowl in carotid atheroscIerosis plaque were lower significantly than those of plaque shoulder(P＜0.05,P＜0.00 1).Conclusions VVI technique could early detect the elasticity degree of blood vessel wall,artherosclerosis and the mechanism asynchrony of the plaque intima.The value difference could be used as the predictive parameter and quantization for artherosclerosis and plaque instability.