MAL gene and its methylation in colorectal carcinoma / 国际外科学杂志
International Journal of Surgery
;
(12): 751-754, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-397649
ABSTRACT
MAL gene expresses in the mediate and late stage of T-lymphocyte,correlated with carcinoma.Hereditary factors and epigenetic mechanisms play important roles in the pathogenesis of colorectal carcinoma.One of the main epigenetic modifications to be identified is methylation of DNA.the hypermethylation and abnormal expressions of MAL gene play a key role in the development,invasion,metastasis and prognosis of colorectai carcinoma.Therefore MAL gene may be another promising early diagnostic marker,which provide new evidence for early stage prediction,classification,prognosis,chemoprevention of colorectal carcinoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
International Journal of Surgery
Año:
2008
Tipo del documento:
Artículo
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