Granulocyte Colony Stimulating Factor for Focal Cerebral Ischemic Injury / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 600-603, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-398680
ABSTRACT
Granulocyte colony stimulating factor(G-CSF)can mobilize hemopoietic stem cells(HSCs)from bone marrow to peripheral circulation,stimulating HSCs and marrow stromal cells(MSCs)homing to the lesion of cerebral ischemia,contributing to the interactions of HSCs and MSCs with the cells in ischemic penumbra,and promoting the generation of neurotrophic factors.G-CSF also has antiapoptotic effect on neurons and drives neurogenesis.Mobilizing autologous HSCs and MSCs using G-CSF for the treatment of local cerebral ischemic injury may reduce the volume of cerebral infarction,and improve neurological functional recovery.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Cerebrovascular Diseases
Año:
2008
Tipo del documento:
Artículo
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