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Application of low-dose glucocorticoids In septic shock / 中国综合临床
Clinical Medicine of China ; (12): 802-804, 2008.
Article en Zh | WPRIM | ID: wpr-399477
Biblioteca responsable: WPRO
ABSTRACT
Objective To study the role of low-dose glucocorticoids in improving prognosis and adjusting septic shock. Methods A total of 46 patients with a confirmed diagnosis of septic shock were retrospaetivley analyzed. 24 patients without glucocorticoids treatment were taken as control group; 22 patients with glucocorticoids as therapy group (n = 22). The two group received standard treatment for septic shock. Results The percentage of shock reversal on day 7 was higher in therapy group than that in control group (P <0.05). However,there were notstatistical significances in the duration of mechanical ventilation, the length of ICU stay, the incidence of multiple or-gan dysfunction syndrome (MODS) and mortality between the two groups (P > 0.05). Conclusion Low-dose glucocorticoids can effectively accelerate refractory septic shock reversal and vasopreasor withdrawal. This seems to be related to the reduced production of CRP but the beneficial effects of low-dose steroids regimens on long-term outcome have not yet be determined.
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Clinical Medicine of China Año: 2008 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Clinical Medicine of China Año: 2008 Tipo del documento: Article