Imaging and clinical diagnosis of reversible posterior leukoencephalopathy syndrome / 中国医师进修杂志

ABSTRACT

Objective To investigate the imaging and clinical characteristics of reversible posterior leukoencephalopathy syndrome (RPLS). Method The imaging and clinical data of 6 patients with RPLS were analyzed retrospectively. Results CT and MRI examination in 6 patients revealed symmetry white matter lesions of occipital lobe in 4 patients, widely white matter edema of fronto-parietal subcortieal white matter in 4 patients, mesencephal and thalamencephal involved in 1 patient, caudate nucleus involved in 1patient. Venous sinus thrombosis was not found in 2 patients of pregnancy-induced hypertension syndrome with magnetic resonance intravenous angiography.All patients were given active treatment,including controlling blood pressure and seizure disorder,dehydration and supporting therapy.The symptom of 5 patients disappeared. One patient left with hemiparesis of right body.Nobody died. Condusion Diagnosis of RPLS isn't difficult as long as clinical history,imaging characteristics and clinical tetrad in the patients of hyperten-sion,eclamptism or renal inadequacy is combined to consider.