The Prevalence of Antimicrobial Resistance in Helicobacter pylori Isolated in Daejeon / 대한임상미생물학회지
Korean Journal of Clinical Microbiology
;
: 47-50, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-40110
ABSTRACT
BACKGROUND:
The most commonly used regimen for the eradication of Helicobacter pylori is combination of a proton pump inhibitor, clarithromycin, and two other antibiotics, metronidazole and amoxicillin. The increase in resistance to antibiotics seems to result in a decrease in eradication efficacy for H.pylori. We investigated the prevalence of antibiotic resistance in H.pylori isolated in Daejeon area.METHODS:
A total of 31 clinical isolates of H.pylori were collected from the patients who underwent upper gastrointestinal endoscopy in Keonyang University Hospital during the period from March to July 2004. Antibiotic susceptibility tests for metronidazole, amoxicillin, and clarithromycin were performed by the E test (AB Biodisk, Sweden) on an egg yolk medium containing triphenyltetrazolium. The resistance break points for amoxicillin, metronidazole, and clarithromycin were defined as 0.5 microgram/mL, 8 microgram/mL, 1 microgram/mL, respectively.RESULTS:
Resistance to amoxicillin, metronidazole, and clarithromycin was detected in 7.4% (2/27), 25.8% (8/31), 3.6% (1/28), respectively.CONCLUSION:
The resistance to amoxicillin and clarithromycin was uncommon in Daejeon area.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacorresistencia Microbiana
/
Prevalencia
/
Endoscopía Gastrointestinal
/
Helicobacter pylori
/
Helicobacter
/
Bombas de Protones
/
Claritromicina
/
Yema de Huevo
/
Amoxicilina
/
Metronidazol
Tipo de estudio:
Estudio de prevalencia
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Clinical Microbiology
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS