Applications of Bone Marrow Stromal Cells in Gene Therapy of Central Nervous System Diseases / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 131-136, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-401911
ABSTRACT
Gene therapy refers to the introduction of normal genes into human target cells for correcting gene defects or exerting therapeutic action,and thus achieves the goal of treatment of disease.Bone marrow stromal cells (BMSCs) are stem cells that possess self-renewal and multi-directional differentiation potential and easy to amplify in vitro,and they also express many therapeutic exogenous genes in vitro or in vivo.So BMSCs have been regarded as an ideal target cell of cell and gene therapy.This article reviews the biological characteristic of BMSCs,some commonly used gene therapy vectors and their applications in gene therapy of central nervous system diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Cerebrovascular Diseases
Año:
2008
Tipo del documento:
Artículo
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