Effect of vacuum sealing drainage and adsorbing material on treatment of large area of skin avulsion wound / 中国组织工程研究

ABSTRACT

BACKGROUND:Skin flap replantation was poor in patients with large area of skin avulsion due to poor blood transportation and severe infection; therefore,dressing should be changed again and again.OBJECTIVE:To investigate the effect of vacuum sealing drainage technology and absorbing materials on the large area of skin avulsion.METHODS:A total-of-100 patients with large area of skin avulsion were selected from Department of Medical Beauty of Affiliated Hospital of Xingtai Medical College between September 1,2008 and August 31,2009.The injury area ranged from 10% to 50%.All patients were randomly divided into odd day group (n=58,testing group which was treated with vacuum sealing drainage) and even day group (n=42,control group which was treated with dressing treatment).Length of stay,infection rates and healing were compared between the two groups.RESULTS AND CONCLUSION:Length of stay in the testing group was significantly shorter than control group (P<0.05).In the testing group,two cases had baumanii infection and 4 had pseudomonas aeruginosa infection,and the infection rate was 10%.In the control group,7 cases had pseudomonas aeruginosa infection and 5 had MRSA infection,and the infection rate was 29%.The infection rate in the testing group was significantly lower than control group (P < 0.05).In the testing group,46 patients (79%) were cured in the first therapy cycle,and the other 12 cases (21%) were treated with autoallergic free skin transplantation; in the control group,12 cases were cured in the first therapy cycle,and the other 30 patients were treated with autoallergic skin transplantation following granulation tissue growing.The secondary operation time in the testing group was significantly shorter than control group (P<0.05).The results suggested that the effect of vacuum sealing drainage technology and absorption materials application were satisfactory in a large area of skin avulsion.