Determination of Menthol in Chuanbei Pipa Syrup by GC / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology
; (6): 361-363, 2009.
Article
en Zh
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| ID: wpr-406467
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ABSTRACT
Objective To test the content of menthol in Chuanbei Pipa Syrup(CPS)by GC, and to evaluate its quality. Meth-ods The content of menthol in CPS was determined by capillary gas chromatography. DB-WAX capillary column (30 m ×0. 319 mm × 0. 50μm) was used with nitrogen as carrier gas. The precolumn pressure was 500 kPa and the column temperature was at 110 ℃ with split ratio of 25 : 1. The temperature was set at 250℃ for sample injection and for the detector. Results The content of menthol in CPS produced by Henan Pharmaceutical Co. , Ltd. , Zhengzhou Pharmaceutical Co. , Ltd. and Yunan Pharmaceutical Co. , Ltd. was 0. 154 mg/mL, 0. 203 mg/mL and 0. 109 mg/mL, respectively. Of them, the men-thol content in CPS produced by Zhengzhou Pharmaceutical Co. , Ltd. met the requirements of Pharmacopoeia(2005 edition), and that of the other two species was slightly lower. Conclusion The methods are convenient, reliable and accurate for the de-termination of menthol content in Chuanbei Pipa Syrup.
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Zh
Revista:
Traditional Chinese Drug Research & Clinical Pharmacology
Año:
2009
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Article