Ultrasonic visualization of splenic autotransplant survival and growth following traumatic splenic rupture / 中国组织工程研究

ABSTRACT

BACKGROUND: Splenic autotransplantation has been presently involved in the treatment of traumatic splenic rupture. Yhere have been retoorts regarding nuclein examination and immunologic test used to monitor splenic autotransplant. But little is known about ultrasonic visualization for follow up of splenic autotransplant. OBJECTIVE: To investigate the value of ultrasonography in monitoring splenic autotransplant survival and growth. DESIGN, TIME AND SETTING: The present retrospective case analysis Was performed at the Department of Ultrasonography. Shenzhen Second People's Hospital between January 2000 and December 2004.PARTICIPANTS:Eighteen patients undergoing splenectomy and suffering from traumatic splenic rupture,13 males and 5 females. aged 20-42 years, were included for this study. METHODS: Non-injured autologous splenic tissue was prepared into thin sections with an area of(2-4)cm×(1-3)cm and a thickness of≤0.5 cm. And transplanted into the greater omentum with abundant vessels in patients undergoing splenectomy.A1118 patients received ultrasonography at 3,6,and 12 months after splenic transplantation, and were subjected to spleen imaging with99Tcm-heat damaged red blood cells. MAIN OUTCOME MEASURES: Nuclein examination of splenic autotransplant survival and growth. RESULTS: Splenic autotransplants survived and gradually grew in 14 of 18 patients. Splenic autotransplants exhibited low level echo similar to normal spleen, regular contour, clear boundary, and visible internal blood flow signal. Splenic autotransplants were not found growing in 4 patients with accessory spleen. CONCLUSION: Ultrasonography can precisely monitor splenic autotransplant survival and growth.