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Expression of CD44 gene nm23 gene TGFα and TNFα in epithelial ovarian cancer / 中国实用妇科与产科杂志
Chinese Journal of Practical Gynecology and Obstetrics ; (12): 155-157, 2001.
Artículo en Chino | WPRIM | ID: wpr-410907
ABSTRACT
ObjectiveTo explore the relation of the expression of intron 9 in CD44 gene,nm23 gene and the serum levels of TGFα and TNFα to the development, metastasis and prognosis of epithelial ovarian cancer. Methods The expressions of intron 9 in CD44 gene, nm23 gene, TGFα and TNFα in epithelial ovarian cancer were measured by semi -quantitative RT - PCR, immunohistochemical technique and radioimmunoassay ( RIA ). Results There was positive expression of intron 9 in CD44 gene,nm23 gene,TGFα and TNFα in 36 cases of epithelial ovarian cancer. The higher levels of nm23 gene and TGFa were obvious in early stage of ovarian cancer. ConclusionTo study the ovarian cancers biologic behavior with these multipe factors can provide theoretical basis for early diagnosis, gene therapy and predicting prognosis.
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: Chinese Journal of Practical Gynecology and Obstetrics Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: Chinese Journal of Practical Gynecology and Obstetrics Año: 2001 Tipo del documento: Artículo