Advances in the study of tumor suppressor genes in gliomas / 中国癌症杂志

ABSTRACT

Glioma is the most malignant tumor in CNS， the effect of present therapy is poor. A important discovery in tumor molecular biology is that the activation of oncogene and inactivation of tumor suppressor gene play an important role in the mechanism of tumorgenesis. The advances in the study of tumor suppressor genes in gliomas were reviewed.