Screening of Phage Display Peptide Libraries Using ComplexBiological Systems as Selector Targets / 生物化学与生物物理进展

ABSTRACT

During recent years, some new methods for phage display panning have been developed by using complex biological systems instead of purified antigens, antibodies or receptors as selector targets. These complex biological systems include living cells, viruses, mouse tissues and tumors etc. The peptides identified by using tumors as selector molecules can selectively home to blood vessels of experimental tumors and may have potential applications in targeted anti-tumor treatment.