Cell Senescence and the Enzyme System for Surveillanceand Repair of DNA Damage / 生物化学与生物物理进展
Progress in Biochemistry and Biophysics
; (12): 37-39, 2001.
Article
en Zh
| WPRIM
| ID: wpr-411744
Biblioteca responsable:
WPRO
ABSTRACT
Senescence is one of the most important phenomena in cells' life. It is hold by one of hypothesis for cell senescence that residue DNA damages of a cell will accelerate its senescence.The normal function of surveillance and repair system for DNA damage is highly related with the senescence regulation of a cell. As a result, research of senescence regulation role of enzymes related for surveillance and repair of DNA damage, such as PARP, DNA-PK, ATM, p53, etc., will discover the inner relation between stress response of cell to DNA damage, regulation of DNA damage repair and cell senescence. That may be helpful for research of anti-aging and treatment of tumor by regulation of senescence of tumor cells.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Progress in Biochemistry and Biophysics
Año:
2001
Tipo del documento:
Article