γ-amino butyric acid transporter and epilepsy / 国际儿科学杂志
International Journal of Pediatrics
; (6): 261-263, 2011.
Article
en Zh
| WPRIM
| ID: wpr-412791
Biblioteca responsable:
WPRO
ABSTRACT
According to 5 different subtypes of γ-amino butyric acid transporter(GAT)in brain regions and subcellular distribution.GAT1 and GAT3 are closely related with occurrence and development of epilepsy.The abnormal expression of GAT or their function damaged contribute to hyperexcitable neurons In seizures.GABAergic inhibit circuit reduces and the down-regulation of GAT expression,primary up-regulation of GAT expression is a reactive changes or cause of epilepsy.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
International Journal of Pediatrics
Año:
2011
Tipo del documento:
Article