The relationship between plasma ghrelin levels and glucose and lipid metabolisms of child and adolescent obesity / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 1306-1307, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-412993
ABSTRACT
Objective To explore the relationship between plasma ghrelin levels and glucose and lipid metabolisms of child and adolescent obesity.Methods 30 cases of obesity and 30 healthy normal weisht children and adolescents with same age and gender were selected.Plasma ghrelin level,serum insulin(INS),C-peptide(CPE),fasting blood glucose(FBG),total cholesterol(TC),triglyceride(TG),high-density lipoproteins(HDL),low-density lipoproteins(LDL)were measured.Results For the obesity groupPlasma ghrelin level significantly decreased [(15.49±1.98)vs(19.47 ±1.50)μg/L]compared with control(P<0.05);BMI,waistline,FBG,INS were very significantly increased(28.19±3.83)vs(21.07±1.53)kg/m2;(88.60±6.13)vs(78.52 ±4.40)cm;(5.23±0.49)vs(4.59 ±0.63)mmol/L;(22.32 ±3.50)vs(16.98±2.50)μIU/ml,respectively compared with control(all P<0.01);TC was significantly increased(5.87±0.88)vs(4.05±0.76)nmol/L compared with control(P<0.05).For the plasma ghrelin level of obesityThe relationship between plasma ghrelin level and body weight,BMI,waistline,INS,TC was obviously negative(r=-0.385,-0.466,-0.336,-0.387,-0.373,respectively,all P<0.01);The relationship between plasma ghrelin level and FBG was obviously negative(r=-0.324,P<0.05);No relationship between plasma ghrelin level and age,body height,CPE,TG,HDLC,LDLC.Conclusion Plasma ghrelin level of children and adolescent obesity was obviously decreased,and was strongly related with disordem of glucose and lipid metabolisms.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Año:
2011
Tipo del documento:
Artículo
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