Progress on the metabolism of antiepileptic drugs by human hepatic CYP3A4 enzymes / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 274-276, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-413266
ABSTRACT
Epilepsy is a common disease in nervous system.Most antiepileptic drugs are metabolized by liver enzymes.such as cytochrome P450 enzyme.CYP3A4 iS the most important enzyme in P450 family.involved in the metabolism of about 40%~60% of the drugs use for clinic.It also has a close relationship with the metabolism of antiepileptie drugs.This review summarizes the general characteristic of CYP3A4 and itsrelationship with the metabolism of antiepileptic drugs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Pediatrics
Año:
2011
Tipo del documento:
Artículo
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