Effect of goal of blood glucose control on protein metabolism in the patients with critically cerebral disease / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6): 8-10, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-415265
ABSTRACT
Objective:
To investigate the effect of three different goals of blood glucose control by insulin therapy on protein metabolism in the patients with critically cerebral disease.Methods:
We performed a prospective,randomized,controlled study.A total of 122 patients with critically cerebral disease were randomly divided into three groups according to the target glucose-control levelsGroup A 4.4-6.1 mmol/L(n=41),Group B 6.1-8.3 mmol/L(n=42),and Group C 10-11.1 mmol/L(n=39).The state of protein metabolism and ratio of hypoglycemia of three groups were compared.Results:
The indicators of nitrogen balance,prealbumin and transferrin in group A and group B were significantly better than that in group C(P<0.05),but the ratio of hypoglycemia in group A was significantly higher than those in group B and group C(P<0.05).Conclusion:
Maintaining the blood glucose level ≤8.3 mmol/L might improve the nutrition status in the patients with critically cerebral disease by decreasing catabolism and promoting synthesis of protein.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Chino
Revista:
Parenteral & Enteral Nutrition
Año:
2010
Tipo del documento:
Artículo
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