Neurovascular unit and poststroke neuroprotection / 国际脑血管病杂志

ABSTRACT

Neurovascular unit is a new paradigm to explore pathophysiology of central nerve system. Its components constitute complex networks for maintaining the steady-state microenvironment of neurons. This article reviews the steady-state changes, related diseases, and neurovascular unit protection among all the components of neurovascular unit, mainly focuses on the neurovascular coupling, ion signal of neurovascular unit, channel regulation, neurovascular regeneration and nutritional factors, as well as the pathological changes of neurovascular unit of ischemic stroke and related control methods.