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Uncoupling protein 4 and its roles in the central nervous system diseases / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases ; (12): 471-475, 2011.
Artículo en Chino | WPRIM | ID: wpr-415847
ABSTRACT
Uncoupling protein 4 (UCP4) is a member of the multigenic uncoupling proteins (UCPs), specific expressing in the cerebral cortex and hippocampus. UCP4 plays an important role in Parkinson's disease, multiple sclerosis, epilepsy, stroke, brain trauma and other central nervous system diseases by uncoupling, decreasing mitochondrial membrane potential,regulating Ca2+ homeostasis and oxidative stress. This article reviews UCP4 and its roles in the central nervous system diseases in order to provide certain basis for the development of UCP4targeted medication.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: International Journal of Cerebrovascular Diseases Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: International Journal of Cerebrovascular Diseases Año: 2011 Tipo del documento: Artículo