Microbial Transformation of Two Prenylated Naringenins
Natural Product Sciences
;
: 306-309, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-41793
ABSTRACT
Microbial transformation of (±)-6-(1,1-dimethylallyl)naringenin (6-DMAN, 1) and (±)-5-(O-prenyl) naringenin-4′,7-diacetate (5-O-PN, 2) was performed by using fungi. Scale-up fermentation studies with Mucor hiemalis, Cunninghamella elegans var. elegans, and Penicillium chrysogenum led to the isolation of five microbial metabolites. Chemical structures of the metabolites were determined by spectral analyses as (±)-8-prenylnaringenin (3), (2S)-5,4′-dihydroxy-7,8-[(R)-2-(1-hydroxy-1-methylethyl)-2,3-dihydrofurano]flavanone (4), (±)-5-(O-prenyl)naringenin-4′-acetate (5), (±)-naringenin-4′-acetate (6), and (±)-naringenin (7), of which 5 was identified as a new compound.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Penicillium chrysogenum
/
Cunninghamella
/
Fermentación
/
Hongos
/
Mucor
Idioma:
Inglés
Revista:
Natural Product Sciences
Año:
2017
Tipo del documento:
Artículo
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