Risk analysis of upper gastrointestinal bleeding in elderly patients with aspirin and clopidogrel co-therapy / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 5-7, 2011.
Article
en Zh
| WPRIM
| ID: wpr-418213
Biblioteca responsable:
WPRO
ABSTRACT
ObjectiveTo explore the current occurrence of upper gastrointestinal bleeding in elderly patients in our hospital and its possible risk factors and treatment program.MethodsAn observational prospective analysis of medical records of 758 consecutive patients was performed.Clinical presentation,etiology and treatment were evaluated.The follow-up ended on the dates of a first occurrence of UGIB,stopping co-therapy,death or 6 months after admitted in the group.Results426 male and 332 female were admitted in the group,UGIB occurred in 48 patients.PPI,H2RA,gastric mucosa protectant plus PPI,gastric mucosa protectant plus H2RA and control were prescribed in 108,240,70,102,238 patients respectively.There were statistics difference in each group compared with control in bleeding rate.ConclusionThe occurrence of UGIB associated with A + C co-therapy in elderly was 6.3%.Co-prescription with PPI and gastric mucosa protectant was associated with a lower risk.
Texto completo:
1
Índice:
WPRIM
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Idioma:
Zh
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Año:
2011
Tipo del documento:
Article