Initial application of virtual touch tissue quantification in diagnosis of chronic allograft nephropathy / 中华超声影像学杂志

ABSTRACT

Objective To investigate the feasibility of virtual touch tissue quantification(VTQ) for the assessment of chronic allograft nephropathy(CAN).Methods 48 patients with normal renal function and 50 patients with CAN were checked by color Doppler and VTQ technique.All the results were compared　between two groups.Results Mean VTQ-values were significantly different between the two groups( P ＜ 0.05).ROC curve displayed that VTQ value of 2.51 m/s could be used to diagnose CAN,the sensitivity,specificity,positive predictive value and negative predictive value were 76.0％,52.1％,60.3％ and 65.7％,respectively.The diagnostic efficiency was 62.2％.Conclusions Parenchymal stiffness measured by VTQ is stable and repeatable,which can be used to diagnose patients with CAN and to monitor renal function.