Clinical value of immunochemical fecal occult blood test in diagnosis of colorectal diseases / 中国医师进修杂志

ABSTRACT

ObjectiveTo discuss the value of immunochemical fecal occult blood test (IFOBT) in diagnosis of colorectal diseases.Methods Two hundred and fifty-one patients who taken IFOBT and chemical fecal occult blood test(CFOBT) from January 2008 to August 2011 were enrolled in this study.They were definitely diagnosed by total colonoscopy combined with pathology.ResultsThe positive rate of IFOBT and CFOBT in colorectal cancer patients was 100.0％(57/57) and 84.2％(48/57),there was significant difference (P ＜ 0.05).The positive rate of IFOBT and CFOBT in colorectal polyp patients was 38.6％ (32/83) and 10.8％(9/83 ),there was significant difference(P ＜ 0.05 ).The positive rate of IFOBT and CFOBT in inflammatory bowel disease patients was 100.0％(31/31) and 80.6％(25/31),there was no significant difference (P ＞ 0.05).Thepositive rate of IFOBT and CFOBT in non-specific enteritis patients were 86.8％ (33/38) and 73.7％ (28/38),there was no significant difference (P ＞ 0.05 ).The positive rate of IFOBT and CFOBT in normal colorectal cases was 2.4％(1/42) and 19.0％(8/42),there was siguificant difference (P ＜ 0.05).ConclusionsIFOBT is better than CFOBT in diagnosis of colorectal cancer and colorectal polyp.IFOBT has lower false positive rate.