mTOR in gastric cancer / 国际肿瘤学杂志

ABSTRACT

Mammalian target of rapamycin (mTOR) is an atypical serine / threonine protein kinase,and belongs to the phosphatidylinositol kinase-related kinase (PIKK) family.mTOR plays an important role in tumor cell growth,apoptosis and tumor angiogenesis. Molecular therapy targeted mTOR has become a hot research topiccurrently.