The use of combination antibiotic theraov in streptococcus pneumoniae infection / 国际儿科学杂志

ABSTRACT

Streptococcus pneumoniae may be the commonest cause of the community acquired pneumonia (CAP).However, the definitive decision regarding the need for combination antibiotic therapy for the effective management of pneumococcal infections has not yet been formally proved, also in the decision regarding the use of beta-lactam/macrolide combination. This review integrated recent studies about adults and children to help to make further understanding in these controversies from these aspects including the impact of the clinical finalresult, the mechanism of combination therapy and the potential problems with the combination therapy.The definitive decision regarding the need for combination antibiotic therapy for the effective management of pneumococcal infections has not yet been formally resolved.