Effect and mechanism of mesenchymal stem cells on cancer cells / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 725-728, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-422146
ABSTRACT
Mesenchymal stem cells (MSCs) not only exhibit a marked tropism for tumors,but also exert antitumorigenic activity or as an emerging vectors to express foreign genes continuously and efficiently within the tumor microenvironment,suppress tumor's growth and metastasis.Conversely,MSCs can accelerate tumor development through promoting tumor stroma remodeling and tumor vascular formation,inhibiting tumor local immune and changing tumor phenotype.The reason for this discrepancy may be attributable to different sources of MSCs,the heterogeneity of MSCs,differences in tumor microenviroment,or another factor that is not yet appreciated.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of International Oncology
Año:
2011
Tipo del documento:
Artículo
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