Serum thymidine kinase 1 measurement in health check-up / 中华健康管理学杂志
Chinese Journal of Health Management
;
(6): 349-352, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-423198
ABSTRACT
Objective To evaluate the utility of serum thymidine kinase 1(STK1)in health screening.Methods A total of 8896 adults who participated in health check-up during November 2009 and November 2010 were tested for STK1 by using sensitive chemiluminescence's dot blot assay.Results The level of STK1 of group A(STK1 > 2 pmol/L)was much higher than that of the group B(STK1 < 2 pmol/L)[(5.47 ±4.23)vs(0.62 ±0.48)pmol/L;t =11.90,P =0.00].The STK1 level was not correlated with gender.However,the mean age of individuals in the group A was higher than that in the group B[(48.2 ± 12.0)vs(41.8 ± 12.3)years; t =5.37,P =0.00].The positive detection rate of STK1 was 1.2%(108/ 8896).In the group A,there were 1.9% pre-or post-treatment malignancy,27.8% pre-malignant tumor or benign disease,36.0% nontumorous proliferation disease,14.8% hepatitis B virus/HP infection,10.2%fatty liver,and 9.3% other diseases.No pre-treatment malignancy and pre-malignancy were found in the group B.Conclusion STK1 measurement could reflect the situation of cell proliferation and predict the risk of any type of malignancy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
/
Estudio de tamizaje
Idioma:
Chino
Revista:
Chinese Journal of Health Management
Año:
2011
Tipo del documento:
Artículo
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