Significance of the high-risk human papilloma virus detection in the screening and diagnosis of cervical lesions / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
;
(36): 7-10, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-426914
ABSTRACT
[Objective]To investigate the significance of the high-risk human papilloma virus (HPV)detection in the screening and diagnosis of cervical lesions.[Methods] The high-risk HPV DNA test results of 797 patients with cervical lesions who all accepted cytology and histopathology test were collected and analyzed retrospectively.[Results]The high-risk HPV DNA positive rates in cervicitis,cervical intraepithelial neoplasia(CIN)Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer were 53.41%(188/352),70.91%(117/165),87.63%(85/97),97.90%(140/143),97.50%(39/40),respectively.The sensitivity and negative predictive value of the high-risk HPV DNA detection for CIN Ⅱ and more serious lesions were 96.66%(318/329),93.29%(153/164),respectively.The detection rate of CIN Ⅱ and more serious lesions in patients with atypical squamous cells of undetermined significance(ASCUS)and positive high-risk HPV DNA was 30.03%(94/313),while the rate in patients with negative high-risk HPV DNA was 1.55%(2/129).[Conclusions] The more serious the cervical lesion is,the higher high-risk HPV DNA positive rate is.It is most closely related with CIN 11 and cervical cancer.The high-risk HPV DNA detection has high sensitivity and negative predictive value for CIN Ⅱ and more serious lesions.The high-risk HPV DNA detection has high negative predictive value in CIN Ⅱ and more serious lesions in ASCUS.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio pronóstico
/
Estudio de tamizaje
Idioma:
Chino
Revista:
Chinese Journal of Postgraduates of Medicine
Año:
2012
Tipo del documento:
Artículo
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