Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases
Genomics & Informatics
;
: 94-101, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-42766
ABSTRACT
tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs made of specific tRNA cleavage. They play regulatory roles in several biological contexts such as cancer, innate immunity, stress responses, and neurological disorders. In this review, we summarize the biogenesis and functions of tRFs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biogénesis de Organelos
/
ARN
/
ARN de Transferencia
/
Enfermedades Neurodegenerativas
/
ARN no Traducido
/
Inmunidad Innata
/
Enfermedades del Sistema Nervioso
Límite:
Humanos
Idioma:
Inglés
Revista:
Genomics & Informatics
Año:
2015
Tipo del documento:
Artículo
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