Postoperative radiotherapy and chemotherapy in cervical cancer / 国际肿瘤学杂志

ABSTRACT

Local recurrence is more frequent in postoperative cervical cancer patients with high-risk factors.It is confirmed that adjuvant pelvic radiotherapy (RT) for the cervical cancer patients after surgery with high-risk factors can improve local control but can't improve the overall survival.Researches show that concurrent chemo-radiotherapy (CCRT) can improve survival rates compared with radiotherapy,but the adverse effects such as leucopenia and gastrointestinal toxicity are observed frequently.Intensity-modulated radiation therapy (IMRT) has been developed to deliver a high radiation dose to an irregular target volume,with relative sparing of adjacent normal tissues.IMRT has excellent local tumor control and overall survival.