Relationship between EphA2 and Laryngeal Carcinoma Angiogenesis / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 2405-2406, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-427891
ABSTRACT
ObjectiveTo study the relationship between EphA2 and laryngeal carcinoma angionegesis.MethodsImmunohistochemical staining was used to determine the expression of EphA2 and CD34 in 20 normal squamous epithelium tissues and 50 laryngeal carcinoma.The relationship between EphA2 expression and Microvascular density was analyzed bg Spearman correlation and linear regression.ResultsThe MVD in laryngeal carcinoma (54.89 ± 13.67) was significantly higher than that in normal squamous epithelial tissues ( 17.15 ± 5.21 ) ; The EphA2 in laryngeal carcinoma(4.56 ± 1.38) was significantly higher than that in normal squamous epithelial tissues ( 2.49 ± 1.23 ) ( t =16.721,5.847,all P < 0.05 ).There was significant positive linear correlation between EphA2 and MVD in laryngeal squamous cell carcinoma(P < 0.01 ).ConclusionEphA2 may correlate with angionegesis in laryngeal squamous cell carcinoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Año:
2012
Tipo del documento:
Artículo
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