PCR-based techniques for the detection of minority mutations / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 40-45, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-431174
ABSTRACT
With the development of molecular biology and molecular genetics,more attention has been taken to the advanced techniques which can be used to detect minority mutations.In recent years,many techniques such as amplification refractory mutation system,PCR clamping,pyrophosphorolysis-activated polymerization,co-amplification at lower denaturation temperature-PCR and digital PCR have been developed,which will make the hereditary disease diagnosis,cancer detection,noninvasive antenatal diagnosis step into a new stage in the near future.This review presents an overview of the principles,aoolications,advantages and disadvantages of these techniques.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Chinese Journal of Laboratory Medicine
Año:
2013
Tipo del documento:
Artículo
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