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A Case Arthritis After Intravesical BCG Instillation for Bladder Cancer / 대한류마티스학회지
The Journal of the Korean Rheumatism Association ; : 192-196, 1995.
Artículo en Coreano | WPRIM | ID: wpr-43150
ABSTRACT
Intravesical instillation of BCG(Calmette-Guerin Bacillus) is the most widely used treatment of superficial transitional cell carcinoma of the bladder. While the exact mechanisms are not yet known, it is assumed that the recognition of tumor antigen is enhanced by immunologic response of the urothelium of mycobacterium. Various complications have been reported after BCG treatment and arthritis is observed in 0.5 to% of treated patients. This from of arthritis may be attributed to an antigen of mycobacterium sharing a cross reactive epitope with an antigen in articular cartilage. A 40-year-old male had transurethral resection and intravesical instillation of BCG for transitional cell carcinoma of bladder. Within few days of the fourth instillation, he developed arthritis on right knee and right metatarsal joint. Laboratory findings showed nonspecific inflammatory sign, positive HLA B27, negative rheumatoid facor and negative antinuclear antibody. The joint effusion was aseptic. He was treated with nonsteroidal antiinflammatory drugs (indomethacin 200rag/day) with resolution of arthritis symptom. We report a patient who developed an inflammatory oligoarthritis following intravesica] instillation of BCG for the treatment oof bladder cancer.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Artritis / Vejiga Urinaria / Neoplasias de la Vejiga Urinaria / Administración Intravesical / Huesos Metatarsianos / Carcinoma de Células Transicionales / Cartílago Articular / Anticuerpos Antinucleares / Urotelio / Inmunoterapia Límite: Adulto / Humanos / Masculino Idioma: Coreano Revista: The Journal of the Korean Rheumatism Association Año: 1995 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Artritis / Vejiga Urinaria / Neoplasias de la Vejiga Urinaria / Administración Intravesical / Huesos Metatarsianos / Carcinoma de Células Transicionales / Cartílago Articular / Anticuerpos Antinucleares / Urotelio / Inmunoterapia Límite: Adulto / Humanos / Masculino Idioma: Coreano Revista: The Journal of the Korean Rheumatism Association Año: 1995 Tipo del documento: Artículo