Simulation analysis of skin hyperthermia with non-isothermal heating / 国际生物医学工程杂志

ABSTRACT

Objective Skin disease is multiple,common disease,and there are so many therapeutic methods.In recent years,physical non-invasive therapy of skin disease has developed rapidly.On the basis of Pennes equation,a series of simulation analysis was completed,and the results confirmed the feasibility and availability as well as the definite safety of curing skin diseases by direct heating.In order to achieve the maximum efficacy and the minimum side effects simultaneously and based on the previous research,exploratory simulation experiment of non-isothermal heating was carried out.Methods The skin temperature fields with non-isothermal heating were simulated by utilizing mathematical tools (Matlab).Results Compared to the previous isothermal heating,during the non-isothermal heating,the temperature of inner skin displayed the rising trend,while it displayed the declining trend during the isothermal heating.Conclusion As compared to isothermal heating,non-isothermal heating has better restraining effect for the bacterium within the inner skin,and less side-effect.