COMPARATIVE ANALYSIS OF TONGUE SQUAMOUS CELL CARCINOMA BETWEEN YOUNG AND OLD PATIENTS / 肿瘤

ABSTRACT

Objective　Tongue cancer shows an increasing frequency in young individuals. There is controversy concerning the clinical course and outcome for oral tongue cancer in young patients.Methods　A retrospective review of 23 patients under 40 years of age with squamous cell carcinoma of tongue was performed. These patients were matched to an older patients group. The 5-year disease-free survival, rates of local, regional and distant recurrence were determined for both groups. Results　The 5-year disease-free survival for the young patients was 68 % versus 74 % in the older group (P＞0.05). 7/23 (30 %) of young patients recurred locally versus 3/23 (14 %) of the older patients (P＞0.05). 6/23 (26 %) of young patients recurred regionally versus 4/23 (18 %) patients in the older group (P＞0.05). The metastatic rates were similar in both groups.Conclusion　In this series, young patients with sguamous cell carcinoma of the oral tongue had a higher locolregional recurrence rate than did older patients. This dose not mean that there is a survival difference.