Observation of Short- and Long-Term Effect of Defibrase on Acute Cerebral Infarction (39 Clinical Cases Report) / 医药导报
Herald of Medicine
;
(12): 305-306, 2001.
Artículo
en Chino
| WPRIM
| ID: wpr-434018
ABSTRACT
To evaluate the short- and long-term effect of defibrase on acute cerebral infarction. Methods:
A prospective, randomized double-blind control method was employed for the study. All the patients were treated with injection of either defibrase or placebo. The scores of neurological function deficits and daily living abilities as well as the level of fibrinogen were tested.Results:
The neurological function of the patients treated with defibrase was significantly improved, the scores of daily living abilities increased, and the level of fibrinogen in blood decreased. A follow-up of the subjects at the time point of one year after the treatment revealed that, the recurrence rate of infarction in those treated with defibrase was zero. Meanwhile, the subjects treated with defibrase had significantly decreased scores of neurological function and significantly improved daily living abilities comparing with those treated with the placebo.Conclusion:
Defibrase can protect the nurons against ischemia-induced lesion, improve the neuron function by decreasing the fibrinogen level. It has valid therapeutic effect on cerebral infarction.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Chino
Revista:
Herald of Medicine
Año:
2001
Tipo del documento:
Artículo
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