Logistic regression analysis on relationship of TCM constitution and impaired glucose regulation and diabetes of 1882 elderly residents of Guangzhou community / 国际中医中药杂志

ABSTRACT

Objective To research community residents TCM constitution and impaired glucose regulation and diabetes,for providing the basis of the community carrying out the adjustment of biased constitution,prevention and treatment of impaired glucose regulation and diabetes.Methods The cross-sectional survey was conducted in Hualin Street,Liwan District,Guangzhou,and 1882 cases of elderly residents over the age of 45 were surveyed on their TCM constitution and blood sugar.According to the Chinese constitution scale survey all cases were divided into gentleness type,yang-deficiency type,qi-deficiency type,dampness-heat type,phlegm-dampness type,yin-deficiency type,qi-depression type,blood-stasis type,and special diathesis type.Divided according to the level of their blood glucose,all cases were classified to normal blood glucose,impaired glucose regulation and diabetes.Logistic regression analysis was conducted to study the relation between TCM constitution and impaired glucose regulation and diabetes mellitus.Results The ratio of phlegm-dampness type in glucose regulation damage and diabetes was much higher than normal blood sugar,the value was 10.07％,19.10％ and 4.98％ respectively.The ratio ofyin deficiency type in diabetes was higher than normal blood sugar,the value was 16.85％and 12.27％,respectively.Compared with gentleness type,a logistic regression analysis model showed that the risk of impaired glucose regulation of phlegm (OR 2.08; 95％CI 1.80 to 2.36) and diabetes (OR 4.39; 95％CI 3.56 to the risk of 5.42) were significantly increased in phlegm-dampness type,and the risk of diabetes (OR 1.62; 95％CI 1.31 to 1.99) was significantly increased in yin deficiency type.Excluded the influence of gender,age,eating habits,the second models showed similar results to the first model,with the phlegm of impaired glucose regulation (OR 1.95,95％CI 1.68 to 2.27),diabetes (OR 4.01,95％CI 3.22 to 5.00),yin deficiency diabetes (OR 1.55,95％CI 1.25 to 1.93) all similar to the first model.Conclusion Phlegm-dampness type and yin-deficiency type are the main TCM constitutions that influencing glucose regulation impairment and diabetes.