Risk factors of nosocomial enterococcal infections / 中华传染病杂志

ABSTRACT

Objective To determine the risk factors of nosocomial infections caused by Enterococcus,and to develop effective protective measures.Methods A retrospective study was conducted among 193 patients who had been infected by Enterococcus from Jan.2011 to Dec.2011 in the First Affiliated Hospital of Anhui Medical University.Clinical data were collected and related risk factors for enterococcal infection were screened.Results The risk factors for enterococcal infection included biliary tract surgery (OR=1.264,95％CI1.141-1.401,P =0.000),drainage tube intubation (OR=1.619,95％CI0.301-4.190,P=0.010),urinary tract intubation (OR=2.001,95％CI1.739-3.803,P 0.000),uses of third generation cephalosporin (OR=2.085,95％CI1.181-3.682,P=0.011) andcarbapenems (OR=1.473,95％CI1.060-2.023,P =0.024).Furthermore,biliary tract surgery (OR=4.861,95％CI3.029-7.802,P=0.000) and urinary tract intubation (OR=2.737,95％CI1.764-4.246,P=0.002) were risk factors for both Enterococcus faecalis and Enterococcus faecium infection,while drainage tube intubation (CR =1.861,95％CI1.702 1.911,P=0.038),uses of the third generation cephalosporin (OR=1.122,95％CI1.022-1.224,P=0.016) and carbapenems (OR=3.051,95％CI1.185-7.855,P=0.021) were independent risk factors for Enterococcus faecium infection.Conclusions Surveillance