Molecular mechanism and regulation in the formation of dextrocardia / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 359-362, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-437370
ABSTRACT
Dextrocardia is formed by the disruption of the normal left-right (L-R) asymmetry of the thoracoabdominal organs.Asymmetric expression of Nodal,Pitx2,Cited2 have affected L-R asymmetry of vertebrate significantly,and generated dextrocardia,mesocardia,ectopia cordis,heterotaxy and so on.Dextrocardia is often accompanied by congenital cardiac malformation.Therefore,it is so difficult to be treated that it has poor prognosis.This paper reveiws the molecular mechanism and it's regulation of dextrocardia for proceeding the genetic diagnosis and early intervention of dextrocardia sequentially in order to improve the survival rate and life quality of patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Pediatrics
Año:
2013
Tipo del documento:
Artículo
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