Research progress of Livin gene in tumors / 国际外科学杂志
International Journal of Surgery
; (12): 762-765, 2013.
Article
en Zh
| WPRIM
| ID: wpr-439040
Biblioteca responsable:
WPRO
ABSTRACT
Livin,as a novel member of human inhibitor of apoptosis protein family,is highly expressed in many malignant tumors.Livin plays critical role in apoptosis inhibition,regulating the cell cycle,participating in tumor angiogenesis.Livin is also significant to chemoresistance.The majority of the current data suggests that Livin expression in cancer appears to be associated with unfavorable clinico-pathological parameters,such as disease relapse and shorter patient survival.In recent years,immunotherapy and gene therapy for the targeting of Livin have become a hot research field,which provides new strategy and direction for tumor therapy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
International Journal of Surgery
Año:
2013
Tipo del documento:
Article