Y-box-binding protein 1 and epithelial-mesenchymal transition / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 896-899, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-439052
ABSTRACT
In the process of epithelial-mesenchymal transition (EMT),cell-cell adherence is disrupted,apico-basal polarity is lost,the ability of anti-apoptosis,migration and invasion is acquired.Y-box-binding protein 1 (YB-1) is a member of the cold-shock protein superfamily,containing a structurally and functionally conserved cold shock domain.Studies indicate that YB-1 can promote the occurrence and development of tumors by regulating EMT.In the process of EMT mediated by YB-1,various transcription factors and signal pathways play important roles.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of International Oncology
Año:
2013
Tipo del documento:
Artículo
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