Bone Union Rate Following Instrumented Posterolateral Lumbar Fusion: Comparison between Demineralized Bone Matrix versus Hydroxyapatite
Asian Spine Journal
; : 1149-1156, 2016.
Article
en En
| WPRIM
| ID: wpr-43911
Biblioteca responsable:
WPRO
ABSTRACT
STUDY DESIGN: Retrospective study. PURPOSE: To compare the union rate of posterolateral lumbar fusion (PLF) using demineralized bone matrix (DBM) versus hydroxyapatite (HA) as bone graft extender. OVERVIEW OF LITERATURE: To our knowledge, there has been no clinical trial to compare the outcomes of DBM versus HA as a graft material for PLF. METHODS: We analyzed prospectively collected data from consecutive 79 patients who underwent instrumented PLF. Patients who received DBM were assigned to group B (n=38), and patients who received HA were assigned into group C (n=41). The primary study outcome was fusion rate assessed with radiographs. The secondary outcomes included pain intensity using a visual analogue scale, functional outcome using Oswestry disability index score, laboratory tests of inflammatory profiles and infection rate. RESULTS: One year postoperatively, bone fusion was achieved in 73% in group B and 58% in group C without significant difference between the groups (p=0.15). There were no differences between the groups with respect to secondary outcomes. CONCLUSIONS: DBM would provide noninferior outcomes compared to the HA as a fusion material for PLF, and could be a notable alternative.
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Índice:
WPRIM
Asunto principal:
Matriz Ósea
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Estudios Prospectivos
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Estudios Retrospectivos
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Durapatita
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Trasplantes
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Hidroxiapatitas
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Asian Spine Journal
Año:
2016
Tipo del documento:
Article