Comparing and analysis of the early-onset and late-onset neonatal sepsis / 中国综合临床
Clinical Medicine of China
; (12): 1336-1339, 2013.
Article
en Zh
| WPRIM
| ID: wpr-439813
Biblioteca responsable:
WPRO
ABSTRACT
Objective To analyse the pathway of infection,risk factors,clinical characteristics and pathogenic bacteria distribution of neonatal sepsis.Methods Eighty-eight neonatal with sepsis were enrooled from January 2006 to December 2011 in the First Affiliated Hospital of Lanzhou University.According to disease stage,they were divided into early-onset sepsis group and late-onset sepsis groups.Results Respiratory infections in two groups was the majority (44.7% vs.46.0%),and there was no significant difference (P =0.906).That premature birth,low birth weight infant,amniotic fluid pollution and asphyxia were risk factors for early-onset sepsis.The most common clinical characteristics in early-onset sepsis were eating less milk(57.9%,22/38) and had fever of the late-onset sepsis(42.0%,21/50).Forty-one cases were with positive blood culture and the rate was 46.6% (41/88),the blood culture specimens were mainly Gram-positive bacteria in two group (75.0% (15/20),90.4% (19/21)).The most common pathogenic bacteria were Staphylococcus aureus and Coagulase-negative staphylococci.Conclusion Premature birth,low birth weight,meconium,asphyxia are risk factors of early onset neonatal sepsis.Early-onset sepsis often shows poor feeding,and late-onset sepsis in children prone to be fever.The common pathogenic germ of early-onset and late-onset sepsis are Grampositivebacteria,Staphylococcus aureus and coagulase-negative staphylococci common.As for neonate with highrisk factors,clinical features of early pathologic examination should be performed in order to further clarify the diagnosis and taking clinical therapy.
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Índice:
WPRIM
Tipo de estudio:
Risk_factors_studies
Idioma:
Zh
Revista:
Clinical Medicine of China
Año:
2013
Tipo del documento:
Article