F-18 Sodium Fluoride Positron Emission Tomography/Computed Tomography for Detection of Thyroid Cancer Bone Metastasis Compared with Bone Scintigraphy
Korean Journal of Radiology
; : 281-288, 2016.
Article
en En
| WPRIM
| ID: wpr-44147
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE: The aim of the study was to compare the diagnostic performances of F-18 sodium fluoride positron emission tomography/computed tomography (bone PET/CT) and bone scintigraphy (BS) for the detection of thyroid cancer bone metastasis. MATERIALS AND METHODS: We retrospectively enrolled 6 thyroid cancer patients (age = 44.7 ± 9.8 years, M:F = 1:5, papillary:follicular = 2:4) with suspected bone metastatic lesions in the whole body iodine scintigraphy or BS, who subsequently underwent bone PET/CT. Pathologic diagnosis was conducted for 4 lesions of 4 patients. RESULTS: Of the 17 suspected bone lesions, 10 were metastatic and 7 benign. Compared to BS, bone PET/CT exhibited superior sensitivity (10/10 = 100% vs. 2/10 = 20%, p = 0.008), and accuracy (14/17 = 82.4% vs. 7/17 = 41.2%, p 0.05). CONCLUSION: Bone PET/CT may be more sensitive and accurate than BS for the detection of thyroid cancer bone metastasis.
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Índice:
WPRIM
Asunto principal:
Fluoruro de Sodio
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Huesos
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Neoplasias Óseas
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Neoplasias de la Tiroides
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Radioisótopos de Flúor
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Tomografía Computarizada por Rayos X
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Estudios Retrospectivos
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Medios de Contraste
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Tomografía de Emisión de Positrones
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Imagen de Cuerpo Entero
Tipo de estudio:
Diagnostic_studies
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Observational_studies
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Korean Journal of Radiology
Año:
2016
Tipo del documento:
Article