Effect of hot compress on reducing oxaliplatin-induced neurotoxicity / 现代临床护理

ABSTRACT

Objective To observe the effects of hot compress on oxaliplatin-induced neurotoxicity.Methods One hundred and twenty patients undergoing chemotherapy with oxaliplatin enrolled in this study were randomly assigned to the control group and expenment group.The control group was given routine health education and the experiment group was treated with hot compress.We compared the incidence of nerotoxocity after 2 and 4 treatment courses.Resulsts The incidence of neurotoxiticity was 75.0%in the experiment group and 91.7%in the control group after 2 treatment courses(P<0.01).The incidences were 86.7%in the experiment group and 98.3%in the control group after 4 treatment courses(P<0.001).Conclusion Hot compress can effectively reduce the incidence of neurotoxicity induced by chemotherapy with oxaliplatin.