The effect of small incision plus tubular stomach on serum VEGF and quality of life in patients with esophageal cancer / 中国基层医药

ABSTRACT

Objective To study the effect of small incision plus tubular stomach on serum vascular endothelial growth factor(VEGF) and quality of life in patients with esophageal cancer.Methods 78 patients with esophageal cancer were randomly divided into two groups,the control group (n =36 cases) and the observation group (n =42cases).The patients in the control group were treated through the conventional operation,while the patients in the observation group were treated through small incision plus tubular stomach.Serum VEGF and quality of life were detected.Results Qualities of life in both two groups were improved after operation and it in the observation group was higher than that in the control group (t =4.36,P ＜ 0.05).Serum VEGF in both two groups were decreased after operation (t =26.11,12.28,all P ＜ 0.01).It in the observation group was lower than that in the control group (t =14.94,P ＜ 0.05).Conclusion Small incision plus tubular stomach can significantly improve serum VEGF and quality of life in patients with esophageal cancer.