A Long Road for Stem Cells to Cure Sick Hearts: Update on Recent Clinical Trials
Korean Circulation Journal
;
: 71-79, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-44518
ABSTRACT
The contribution of stem cells to cure damaged hearts has finally been unraveled. A large number of preclinical and clinical studies have showed beneficial outcomes after myocardial infarction. In this review, the current understanding of stem cell therapy in preclinical and clinical experiences is summarized. Stem cells from bone marrow have shown a potential to improve cardiac performance after myocardial infarction in animal and early clinical studies. Clinical trials from all over the world have provided safety assessments of stem cell therapy with marginal improvement of clinical outcomes. Thus, further investigations should be encouraged to resolve the discrepancies between studies, clinical issues, and unclear translational findings. This review provides information and commentary on key trials for stem cell-based treat-ment of cardiovascular disease.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Madre
/
Médula Ósea
/
Enfermedades Cardiovasculares
/
Revisión de la Investigación por Pares
/
Experimentación Animal
/
Corazón
/
Infarto del Miocardio
Límite:
Animales
Idioma:
Inglés
Revista:
Korean Circulation Journal
Año:
2012
Tipo del documento:
Artículo
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