The study of the potassium ion channel Kv 3 .4 in buccal mucosa carcinogenesis of rat / 重庆医学
Chongqing Medicine
;
(36): 1837-1839, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-447531
ABSTRACT
Objective To investigate the expression of the Kv3 .4 protein and Kv3 .4 mRNA in various stages of oral carcino‐genesis .Methods The expression of Kv3 .4 protein and Kv3 .4 mRNA were detected by immunohistochemistry (SP method) and RT‐PCR technique respectively in the oral carcinogenesis of SD rat which were induced by 4NQO .Results With the aggravation of the epithelial dysplasia ,Kv3 .4 protein and Kv3 .4 mRNA expression increased gradually .They were strongly positive in oral squa‐mous cell carcinoma .Conclusion The expression of Kv3 .4 protein and Kv3 .4 mRNA levels increased consistently with the aggra‐vation of the epithelial dysplasia .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chongqing Medicine
Año:
2014
Tipo del documento:
Artículo
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